[The effect of initial periodontal therapy on metabolic control in type 2 diabetes mellitus.]

PURPOSE: To investigate the effect of periodontal initial therapy on metabolic control in type 2 diabetes mellitus patients with chronic periodontitis. METHODS: Thirty type 2 diabetic patients with chronic periodontitis were selected as experimental group, 30 patients with chronic periodontitis were selected as control group. Their gingival index(GI), probing depth(PD), clinical attachment level(CAL), fasting plasma glucose(FPG), glycated hemoglobin A1c(HbA1c), total cholesterol(TC) and triglyceride(TG) were evaluated using SAS 6.12 software package for multiple linear regression analysis before treatment(as base) and 1, 3 month(s) after periodontal initial therapy. RESULTS: In both two groups, a significant improvement of periodontal index was found after periodontal initial therapy (P<0.05). After therapy, TC, TG in diabetic patients showed no changes(P>0.05), and FPG, HbA1c in fairly-controlled diabetic patients were reduced significantly(P<0.05) whereas the well-controlled diabetic patients showed slight but insignificant decrease for these parameter(P>0.05). CONCLUSION: The result of periodontal initial therapy in the type 2 diabetic patients with chronic periodontitis is significant in short time. It can reduce the level of FPG and HbA1c. Supported by National Key Science and Technology Project from \”Tenth Five Year Plan\” (Grant No.2004BA720A26).

Shen CJ, Yin YZ, Shu R.

Department of Periodontics, College of Stomatology, Ninth People\’s Hospital, School of Medicine, Shanghai Jiao Tong University; Shanghai Research Institute of Stomatology. Shanghai 200011, China.E-mail:yyz99@citiz.net.