BIOMEDICAL ARTICLES
Long-term plasma levels and dose modulation of alacepril in patients with chronic renal failure.
Because most angiotensin-converting enzyme inhibitors are excreted into urine, any decrease in renal function increases the plasma levels of these drugs. This study was designed to investigate the appropriate doses of alacepril in patients with chronic renal failure. The […]
Valsartan Amlodipine Randomized Trial (VART): Design, Methods, and Preliminary Results.
Antihypertensive therapy has been well established to reduce hypertension-related morbidity and mortality, but the optimal therapy for Japanese patients remains unknown. The Valsartan Amlodipine Randomized Trial (VART), a prospective randomized open-label trial, was designed to determine whether treatment with an angiotensin II type […]
Interventricular septum thickness predicts future systolic hypertension in young healthy pilots.
Left ventricular hypertrophy (LVH) has been associated with hypertension, although debate exists as to whether LVH is caused by elevated blood pressure (BP) or is a risk factor for its development. The present study evaluates the association between left ventricular structure and […]
Comparison of effects of olmesartan and telmisartan on blood pressure and metabolic parameters in Japanese early-stage type-2 diabetics with hypertension.
Angiotensin II type-1 receptor blockers (ARBs) are regarded as first-line treatments for type-2 diabetes with hypertension. Despite the availability of various types of ARBs, there are no comparative studies of their effects on […]
Cerebral White Matter Lesions and Microbleeds: Tiny but Meaningful Indicators of Hypertensive Damage.
(Hypertens Res 2008; 31: 5-6).
Toyoda K.
Cerbrovascular Division, Department of Medicine, National Cardiovascular Center.
Aegis against Stroke and Dementia by Angiotensin Type 1 Receptor Blockers: New Beneficial Aspects.
(Hypertens Res 2008; 31: 1-3).
Morishita R.
Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University.
Mechanism of Estruction of Microtubule Structures by 4-Hydroxy-2-Nonenal.
A major end product of lipid peroxidation, 4-hydroxy-2-nonenal (HNE), is an electrophilic alkenal and produces Michael adducts with cellular proteins. It is known that exposure of cultured cells to HNE causes rapid disappearance of microtubule networks. In this study we addressed the mechanism. Immunochemical studies […]
ATF6 is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum.
Eukaryotic cells cope with endoplasmic reticulum (ER) stress by activating the unfolded protein response (UPR), a coordinated system of transcriptional and translational controls, which ensures the integrity of synthesized proteins. Mammalian cells express three UPR transducers […]
Observations on ozone treatment of excess sludge.
We regret that the list of authors\’ addresses for this paper was printed with an incorrect mailing address introduced for the corresponding author, J. Yin; the correct details are as given here.
Yin J.
School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin, 150090, […]
Fouling and its reversibility in relation to flow properties and module design in aerated hollow fibre modules for membrane bioreactors.
Nowadays, most membrane bioreactors are using membranes submerged in the biomass and aeration in the concentrate compartment to limit or to control fouling. An important issue for the design of modules or membrane […]
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