BIOMEDICAL ARTICLES
[Effect of photodynamic therapy on IL-1beta and MMP-8 in gingival crevicular fluid of chronic periodontitis.]
PURPOSE: Photodynamic therapy (PDT) is used in infectious disease for its antimicrobial effects. The aim of the study is to evaluate the effects of a diode laser-based photodynamic therapy on the treatment of chronic periodontitis. METHODS: Fifty eight […]
[The effect of initial periodontal therapy on metabolic control in type 2 diabetes mellitus.]
PURPOSE: To investigate the effect of periodontal initial therapy on metabolic control in type 2 diabetes mellitus patients with chronic periodontitis. METHODS: Thirty type 2 diabetic patients with chronic periodontitis were selected as experimental group, 30 patients with chronic […]
Evaluation of Cetuximab in combination with radiotherapy or chemotherapy against advanced squamous cell carcinoma of the head and neck.
Cetuximab is an epidermal growth factor receptor inhibitor which has been recently focused on the therapy of squamous cell carcinoma of the head and neck based on the nearly universal expression of this protein, […]
Restless leg syndrome: is it a real problem?
Restless legs syndrome (RLS) is a common condition that is frequently unrecognized, misdiagnosed and poorly managed. It is characterized by uncomfortable sensations deep in the legs developing at rest that compel the person to move; symptoms are worst at night and sleep disturbance is common. […]
Update on the appropriate use of linezolid in clinical practice.
Multi-antibiotic resistant Gram-positive cocci, which include Staphylococcus aureus, the coagulase-negative staphylococcal group, Enterococcus faecalis and Enterococcus faecium, and other streptococci, represent emerging pathogens especially in the setting of the immunocompromised, hospitalized patients, in particular when surgery, invasive procedures, or prosthetic implants are of […]
Optimizing use of opiates in the management of cancer pain.
Cancer pain is often suboptimally managed. The underestimation and undertreatment continues to be a problem despite the availability of consensus-based guidelines. Most patients with cancer develop pain. The prevalence and severity of pain among cancer patients varies according to primary and metastatic sites […]
Role of erlotinib in the management of pancreatic cancer.
Pancreatic cancer is a largely chemo-resistant disease with a poor prognosis. Despite the adoption of gemcitabine monotherapy as a standard of care, outcomes remain poor. Until recently randomized phase III studies have not demonstrated superiority of various cytotoxic combinations or a number of the […]
Moxifloxacin in the treatment of skin and skin structure infections.
Moxifloxacin is a recent addition to the fluoroquinolone class, differing from ciprofloxacin and other older agents in having much better in vitro activity against Gram-positive aerobes while retaining potent activity against Gram-negative aerobes. It is also active against the pathogens of human and […]
Meropenem in the treatment of complicated skin and soft tissue infections.
Meropenem is a broad-spectrum carbapenem antibiotic with excellent activity against many pathogens associated with complicated skin and soft tissue infections (cSSTIs). At least three studies have shown meropenem to have good clinical efficacy and to be well tolerated in the treatment of […]
Infliximab (Remicade) in the treatment of psoriatic arthritis.
Elucidation of the cellular immunopathology and cytokine profile of psoriatic arthritis (PsA), a chronic inflammatory disease associated with psoriasis, has resulted in the development of a number of novel biologic therapies. Among these biologics, tumor necrosis factor-alpha (TNF-alpha) inhibitors have been used successfully to treat […]
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