BIOMEDICAL ARTICLES
Elective open abdominal aortic aneurysm repair: a seven-year experience.
INTRODUCTION: The seven-year experience of elective abdominal aortic aneurysm (AAA) repair of a vascular surgical unit in a teaching hospital was reviewed to determine the factors associated with in-hospital mortality. METHODS: All patients who underwent elective open repair of an AAA between July 1, […]
Should valproate be taken during pregnancy?
The Australian Registry of Antiepileptic Drug Use in Pregnancy includes 172 instances in which women took sodium valproate, with or without other antiepileptic drugs, during pregnancy. These pregnancies resulted in a substantially higher (p < 0.05) rate of malformed offspring (15.1%) compared with 348 pregnant women who […]
Principles in genetic risk assessment.
Risk assessment constitutes an essential component of genetic counseling and testing, and the genetic risk should be estimated as accurately as possible for individual and family decision making. All relevant information retrieved from population studies and pedigree and genetic testing enhances the accuracy of the assessment of an […]
Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4.
Mechanism-based inhibition of cytochrome P450 (CYP) 3A4 is characterized by NADPH-, time-, and concentration-dependent enzyme inactivation, occurring when some drugs are converted by CYPs to reactive metabolites. Such inhibition of CYP3A4 can be due to the chemical modification of the heme, the […]
Editorial foreword.
Walsh G.
Asthmatic and Allergic Inflammation Group, School of Medicine, University of Aberdeen UK.
The foundational model of anatomy in OWL: Experience and perspectives.
We present the method developed for migrating the Foundational Model of Anatomy (FMA) from its representation with frames in Protégé to its logical representation in OWL and our experience in reasoning with it. Despite the extensive use of metaclasses in Protégé, it proved […]
Copolymerization and Dark Polymerization Studies for Photopolymerization of Novel Acrylic Monomers.
The copolymerization behavior and the dark polymerization kinetics of highly reactive novel acrylic monomers were compared to traditional acrylate monomers. Copolymerization of thiol functionalities with novel acrylic monomers was characterized, and it was observed that the inclusion of secondary functionalities such as […]
Ultrasensitive absorption spectroscopy with a high-finesse optical cavity and off-axis alignment.
A simple and easy to use method that allows high-finesse optical cavities to be used as absorption cells for spectroscopic purposes is presented. This method introduces a single-mode continuous-wave laser into the cavity by use of an off-axis cavity alignment geometry to […]
Diode-Laser Wavelength-Modulation Absorption Spectroscopy for Quantitative in situ Measurements of Temperature and OH Radical Concentration in Combustion Gases.
The in situ quantitative profiles of temperature and OH radical concentration in a postflame region of methane-air premixed counterflow flames were measured by wavelength modulation spectroscopy with a 1.5-mum external cavity diode laser. The second […]
Shape of the particulate beam attenuation spectrum and its inversion to obtain the shape of the particulate size distribution.
The link between the spectral shape of the beam attenuation spectrum and the shape of the particle size distribution (PSD) of oceanic particles is revisited to evaluate the extent to which one can be […]